Smoking can significantly reduce the effectiveness of Fildena CT 50, a medication used to treat erectile dysfunction. The active ingredient in Fildena CT 50 mg is sildenafil citrate, which works by increasing blood flow to the penis through the relaxation of blood vessels. However, smoking causes vasoconstriction, narrowing blood vessels and restricting circulation, which directly counters sildenafil’s mechanism of action. Additionally, the chemicals in tobacco can damage the lining of blood vessels, impairing nitric oxide production—an essential component for achieving an erection. Smoking also contributes to chronic health issues like cardiovascular disease and reduced oxygenation, further weakening sexual performance and the drug’s efficacy.