Cenforce D is a medication commonly used to treat erectile dysfunction (ED) and premature ejaculation. However, it may not be advisable to take it in the following situations:

1. Allergic Reaction: If you have a known allergy to any of the active ingredients, such as sildenafil or dapoxetine, you should avoid taking Cenforce D.

2. Heart Conditions: If you have heart issues such as severe heart disease, irregular heart rhythms, or a recent history of heart attack or stroke, you should avoid Cenforce D, as it can put extra strain on the heart.

3. Low Blood Pressure (Hypotension): Cenforce D may cause a drop in blood pressure. If you have low blood pressure or are on medications to treat it, taking Cenforce D may exacerbate this problem.

4. Severe Liver or Kidney Disease: If you have liver or kidney conditions that are severe or uncontrolled, this could affect how the drug is processed in your body, leading to potential complications.